A victory by the Arizona Cardinals over the Carolina Panthers is our computer model prediction for these teams’ upcoming game, on Sunday, Dec. 22 at 1 p.m. ET (at Bank of America Stadium). For a full breakdown, including the spread, over/under and final score, continue reading.

Looking for NFL tickets? Head to StubHub today and see your team live.

The Cardinals are averaging 351.4 yards per game on offense, which ranks them 11th in the NFL. On the defensive side of the ball, they rank 17th, giving up 338.4 yards per game. The Panthers have plenty of room to improve, as they rank second-worst in total yards per game (288.9) and second-worst in total yards surrendered per game (386.2).

BetMGM is one of the most trusted Sportsbooks in the nation. Start with as little as $1 and place your bets today.

Panthers vs. Cardinals Predictions and Picks

Ready to make your pick? Head to BetMGM using our link and start betting today.

Panthers Betting Info

• The Panthers have a 34.5% chance to win this game based on the implied probability of the moneyline.
• Carolina has compiled a 6-8-0 ATS record so far this year.
• The Panthers have been an underdog by 5 points or more nine times this year, and covered the spread in six of those contests.
• So far this season, 10 of Carolina’s 14 games with a set number have gone over the point total.
• Games involving the Panthers this year have averaged 43.3 points per game, a 3.7-point differential when compared to the over/under for this contest.

Watch this game on Fubo (Regional restrictions may apply)

Cardinals Betting Info

• Based on this matchup’s moneyline, the Cardinals’ implied win probability is 71.4%.
• Arizona is 9-5-0 ATS this season.
• The Cardinals have been favored by 5 points or more once this season, and covered the spread.
• Arizona games have gone over the point total six out of 14 times this season.
• The over/under for this game is 47 points, 0.2 more than the average point total for Cardinals games this season.

Rep your favorite NFL players with officially licensed gear. Head to Fanatics to find jerseys, shirts, hats, and much more.

Panthers vs. Cardinals 2024 Scoring Insights

Catch every NFL touchdown with NFL RedZone on Fubo.

Not all offers available in all states, please visit BetMGM for the latest promotions for your area. Must be 21+ to gamble, please wager responsibly. If you or someone you know has a gambling problem, contact 1-800-GAMBLER.